Epidermolysis Bullosa – Tread Carefully!!

Patients with epidermolysis bullosa (EB) provide a unique and complex challenge for the anaesthesiologist. This is rare inherited group of diseases characterized by excessive fragility skin mucous membranes. These patients tolerate compressive forces to but barely friction shearing forces. Major challenges anaesthetist include establishing adequate monitoring without damaging skin, issues positioning, high possibility difficult airway, compromised immunity nutritional deficiencies, other comorbidities. We present case 4-month-old baby boy simplex presented blisters ulcers all over body, posted thoracoscopic plication diaphragmatic eventration. highlight that meticulous preoperative planning extreme attention prevent any or frictional forces, anaesthesia can be delivered safely.